Economic Development

Press Enter to show all options, press Tab go to next option


From attracting the  largest and fastest growing biotechnology companies in the world to assisting small local businesses, the City of South San Francisco offers support for business development and economic growth opportunities that support a strong and sustainable future for the City and its residents.

Within South San Francisco there are currently many opportunities for entrepreneurs to begin new development, relocate current projects and start new endeavors. Please check our website frequently for new development opportunity sites offered by the City of South San Francisco.

Opportunities and Development

Development Opportunities offered by the City of South San Francisco

Commercial and Industrial Listings in South San Francisco

SSF Interactive Zoning Map

South San Francisco Long Range Property Management Plan

Construction Updates

Current Development Activity 

The following are major development projects at various stages of the City’s review process or construction phase. For a full list of construction and development projects in the City click here.


 Office/R&D Projects
494 Forbes Blvd
249 E. Grand Office/R&D
328 Roebling
Merck Campus
475 Eccles
Gateway Business Park Master Plan
Gateway of Pacific
Britannia Cove at Oyster Point
Oyster Point Redevelopment


A. Phase IC and Phase ID


B. Phases IID - IVD


C. Phase IIC

Genentech Childcare Facility
Genetech Building B-40
USDA Office Building



Commercial Projects

 Costco Site Improvements

Costco Business Center
550 Gateway Hotel
Marriott Fairfield Inn & Suites
Days Inn
Park SFO Expansion
Circle K
840 El Camino Real
479 South Airport Blvd



Civic Projects
Caltrain Station Improvement Project
SSF Community Civic Center Campus